Device built-in

Thermo Scientific Automated Dispenser & Dispense Cassette System - Product Introduction

The Thermo Scientific Multidrop Combi/SMART Automated Dispenser is a core instrument designed for high-throughput drug screening, genomics, and proteomics research, featuring ultra-wide dispensing range (0.5 μL–2500 μL), multi-plate compatibility (6-well to 1536-well plates), and an intelligent dispense cassette system to significantly enhance experimental efficiency and data reliability.

I. Core Features of Automated Dispenser

1. Flexible Dispensing Control

   • Supports customizable column/volume dispensing with automatic height adjustment (5–50 mm), optimized for cells, viscous solutions, etc.
   • Ultra-fast dispensing: 96-well plate (20 μL/well) in just 4 seconds, with throughput up to 300 plates/hour in high-throughput mode.

2. High Precision & Automation

   • Dispensing precision: CV≤1.5% at 20 μL, CV≤1% at 100 μL, ideal for 384/1536-well miniaturized assays.
   • Integrates via RS232/USB with automation systems, compatible with robotic arms and RapidStak plate stackers.

3. SMART Technology

   • RFID-tracked cassette usage ensures quality control compliance, particularly for GMP/GLP environments.

II. Dispense Cassette System

1. Three Cassette Types

   • Standard Cassette (5–2500 μL): For cells, beads, and aqueous solutions; dead volume <7 mL.
   • Fine Tip Plastic Cassette (0.5–50 μL): For low-volume aqueous solutions; CV≤5%.
   • Fine Tip Metal Cassette (0.5–50 μL): Designed for proteins/viscous solutions to prevent liquid column bending; autoclavable at 121°C.

2. Low-Consumable & Sterile Design

   • Drain-back function minimizes reagent waste; cassettes are sterilizable to prevent cross-contamination.

III. Key Applications

• Drug Screening: High-throughput compound storage and ELISA assays.
• Cell Culture: Dispensing >20 cell lines (e.g., HEK293) without viability impact.
• Microbiology: Bacterial/fungal cultures and Drosophila embryo dispensing.

Technical Advantages

The Multidrop Combi excels in flexibility, speed, and precision, combined with SMART cassettes' traceability, making it ideal for biopharma and CRO labs.

Fields of Use: Pharmaceutical companies, research institutes, CDC (e.g., Shenyang Animal Disease Control Center).
Options: RapidStak integration module, multi-cassette kits.

(Note: "Multidrop Combi" and "SMART" are registered trademarks of Thermo Fisher Scientific.)

References:

1. Thermo Scientific Multidrop Combi Product Manual
2. GLP Compliance Guidelines for Automated Liquid Handlers
3. High-Throughput Screening Applications in Drug Discovery (2023)

(Translated with technical accuracy, retaining all specifications and proprietary terms per manufacturer guidelines.)