Device built-in

Cytiva AKTA process Protein Purification System – Introduction (Brief Overview)

The AKTA process protein purification system by Cytiva is an automated chromatography platform designed for industrial-scale protein purification, process development, and production-scale biopharmaceutical manufacturing. Below is a concise overview of its key features:

1. System Overview

The AKTA process is a large-scale purification system, engineered for high-capacity protein purification (gram to kilogram scale). Compared to lab-scale systems like AKTA avant or AKTA pure, it offers higher flow rates, pressure tolerance, and scalability for industrial applications.

2. Key Features

• High Flow Rate & Scalability: Supports flow rates up to 150 mL/min (e.g., AKTA avant 150 model), enabling seamless process scale-up from lab to production.
• Automation & Compliance: Integrated UNICORN™ control software for DoE (Design of Experiments), data tracking, and GMP-compliant operations.
• BufferPro™ Automated Buffer Preparation: Reduces manual errors and improves efficiency with in-line buffer blending.
• Fraction Collection with Cooling: Equipped with Peltier-cooled fraction collectors to maintain sample stability.

3. Applications

• Antibody & Vaccine Production: Purification of monoclonal antibodies (mAbs), recombinant proteins, and viral vectors.
• Process Development & Scale-Up: Enables linear scale-up from small-scale optimization to full production.

4. Key Advantages

The AKTA process system delivers high reliability, automation, and industrial-grade performance, integrating seamlessly with Cytiva’s chromatography resins (e.g., HiTrap columns) for end-to-end bioprocessing solutions.

For detailed specifications or application examples, further information can be provided upon request.

Note:

• "思拓凡" is translated as Cytiva (its global brand name).
• AKTA process retains its original name as it is a trademarked product line.
• Technical terms (e.g., UNICORN™, BufferPro™) follow Cytiva’s official nomenclature.