Device built-in

Waters Xevo TQ-XS Triple Quadrupole Mass Spectrometer Product Introduction

Core Technological Innovations
The Waters Xevo TQ-XS is a high-performance triple quadrupole LC-MS/MS system featuring StepWave XS off-axis ion optics technology. Its segmented quadrupole design actively eliminates neutral interferences, improving ion transmission efficiency by 2-10x and delivering superior signal-to-noise ratios compared to conventional systems. With a mass range of 2-2,000 m/z and a linear dynamic range spanning 6 orders of magnitude, it achieves femtogram-level detection sensitivity while maintaining excellent reproducibility—even for low-concentration or unstable analytes.

Key Technical Features

1. Tool-Free Maintenance: Proprietary quick-release ion source enables routine servicing in under 2 minutes, minimizing operator-dependent variability.
2. UniSpray™ Hybrid Ion Source: Simultaneously supports ESI/APCI/APPI modes in a single run, enhancing response for compounds with diverse polarities (e.g., antibiotics, hormones).
3. XDR™ Detector: Resolves concentration disparities within samples, eliminating the need for multiple dilutions in traditional workflows.

Primary Applications

• Food Safety: High-throughput screening of 78 veterinary drug residues (e.g., sulfonamides, quinolones) in 10 minutes, compliant with GB 31650-2021 standards.
• Environmental Monitoring: Direct injection analysis of PFAS in water with 0.1 ng/L detection limits, requiring no sample preparation.
• Biopharmaceuticals: Intact mass analysis of monoclonal antibodies and metabolite identification across pg/mL to μg/mL concentration ranges.

System Configuration

• Hardware: Standard Turbo V™ dual-spray ion source (ESI/APCI); optional APGC interface for gas-phase applications.
• Software: MassLynx® 4.2 with QUANPEDIA™ database, supporting SWATH® DIA and MRMHR quantification.

ISO/IEC 17025 certified, this instrument has been adopted by Tsinghua University for emerging contaminant research. Its data quality meets international pharmacopoeia standards. The 2025 base configuration starts at approximately ¥1.4 million RMB (customizable).

(Note: "StepWave XS", "UniSpray", and "XDR" are Waters technologies. Performance claims reflect manufacturer testing.)

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