Device built-in
Analytik Jena Real-Time PCR Systems Technical Overview
Core Technological Innovations
Analytik Jena's qTOWER series (including qTOWER3 G and qTOWERiris models) feature four-channel solid-state LED excitation (blue/green/red/white) combined with fiber-optic scanning detection, covering 360-730nm full spectrum for 6-channel simultaneous detection with single-copy DNA sensitivity. The gold-plated pure silver sample block achieves ±0.1°C temperature uniformity at 8°C/s ramp rates, with ±0.15°C well-to-well consistency for enhanced amplification specificity.
Modular Functional Design
- Flexible Detection: 12 configurable filter sets support FRET probes and protein melt curve analysis (SYPRO Orange/CPM dyes) for nucleic acid/protein dual applications.
- Advanced Thermal Control: Patented linear temperature gradient (1-40°C across 12 columns) enables rapid annealing optimization for 5-80μL reaction volumes.
- Smart Software: MIQE-compliant qPCRsoft software integrates absolute quantification, SNP genotyping, and amplification efficiency analysis with 21 CFR part 11 compliance.
Industry-Proven Applications
- Precision Medicine: >80% gene editing efficiency in CAR-T therapy; 2 copies/μL sensitivity for pathogens (e.g., SARS-CoV-2).
- Synthetic Biology: High-resolution melting (HRM) analyzes SNPs with CV<0.07 reproducibility.
- Protein Studies: qTOWERiris UV channel specializes in membrane protein thermal stability (CPM/ANS compatible).
Technical Specifications
- Optics: 6-channel PMT detector, 4s/96-well scanning
- Throughput: 40-cycle runs in 40 minutes (96-well)
- Certifications: ISO 13485/CE with 10-year optics warranty
Adopted by Roche and Novartis, the 2025 base models are priced at ¥500,000-800,000 RMB.
(Note: "qTOWER" and "qPCRsoft" are Analytik Jena trademarks. Performance claims based on manufacturer testing.)
For application notes or regional service inquiries, please contact authorized distributors.