Device built-in

Introduction to GE Cytiva AKTA avant 150 Protein Purification Chromatography System

1. Product Overview
The GE Cytiva AKTA avant 150 is a high-performance, flexible, medium-to-low-pressure chromatography system designed for laboratory-scale protein purification. It is widely used in research, biopharmaceutical development, and process optimization, catering to needs ranging from small-scale screening to process scale-up. Combining automated control, precise fluid handling, and intelligent software, the ÄKTA avant 150 delivers consistent and reproducible purification results.

2. Key Features

• Modular Design: The system features a modular structure, allowing flexible configuration of pumps, detectors, and fraction collectors to meet diverse experimental requirements.
• High-Precision Fluid Handling: Equipped with an accurate piston pump, it offers a wide flow rate range (0.001–150 mL/min) for stable chromatographic separation.
• Multi-Wavelength UV Detection: Supports detection at 200–700 nm, enabling simultaneous monitoring of multiple wavelengths for enhanced data accuracy.
• Intelligent Software Control: Utilizes UNICORN™ control software, providing an intuitive interface for method development, data analysis, and report generation.
• Broad Compatibility: Suitable for various purification techniques, including affinity chromatography, ion exchange, hydrophobic interaction, and size exclusion chromatography.

3. Applications
The ÄKTA avant 150 is widely used in biopharmaceuticals, vaccine development, antibody purification, and recombinant protein production, particularly for:

• Laboratory-Scale Protein Purification: Such as monoclonal antibodies, enzymes, and vaccine antigens.
• Process Development & Optimization: Facilitates small-scale process screening to provide reliable data for scale-up production.
• Academic & Research Use: Ideal for protein purification experiments in universities and research institutes.

4. Technical Advantages

• High Reproducibility: Precise flow control and stable pressure management ensure reliable experimental results.
• High Automation: Supports automated sample injection, gradient elution, and fraction collection, minimizing manual errors.
• Low Sample Consumption: Optimized flow path design reduces dead volume and improves sample recovery.
• Regulatory Compliance: Meets GMP/GLP standards, making it suitable for regulated drug development environments.

5. Conclusion
The GE Cytiva ÄKTA avant 150 is a high-performance, user-friendly, and scalable protein purification system, ideal for research and bioprocess development. Its modular design, intelligent software, and robust performance make it a preferred choice for laboratory-scale protein purification. Whether for basic research or industrial process development, the ÄKTA avant 150 provides efficient and reliable purification solutions.

For detailed technical specifications or application case studies, please refer to GE Healthcare (Cytiva) official documentation or contact authorized distributors.