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Thermo Scientific™ Orbitrap Fusion™ Lumos™ Mass Spectrometer with ETD - Product Introduction

Product Overview
The Thermo Scientific™ Orbitrap Fusion™ Lumos™ mass spectrometer with Electron Transfer Dissociation (ETD) capability represents the ultimate solution for proteomics, post-translational modification (PTM) analysis, and biopharmaceutical research. This system integrates Orbitrap, ion trap, and ETD technologies to deliver the most comprehensive coverage for complex biological sample analysis.

Core Technological Advantages

1. Revolutionary Resolution

   • Orbitrap mass analyzer provides resolution up to 500,000 (at m/z 200)
   • Mass accuracy <1 ppm, enabling isotopic fine structure differentiation

2. Multi-Dimensional Fragmentation

   • Standard configuration includes HCD/ETD/CID dissociation modes
   • ETD functionality is particularly optimized for PTM analysis (e.g., phosphorylation, glycosylation)

3. Ultra-High Sensitivity

   • Advanced Quad Filter Technology enhances signal intensity by 10-fold
   • Detection capability down to zeptomole levels

Key Applications

• Proteomics: Large-scale protein identification and quantification
• Biopharmaceuticals: Characterization of antibody-drug conjugates (ADCs)
• Clinical Research: Biomarker discovery and validation

System Configuration

• Ion Source: Nano-electrospray ionization (nESI)
• Detectors: High-energy C-Trap and Dual-Pressure Linear Ion Trap
• Software Platform: Thermo Scientific™ Proteome Discoverer™ 2.5

Certified under ISO 9001 and compliant with FDA 21 CFR Part 11 requirements, this system has become the platform of choice for leading research institutions and pharmaceutical companies worldwide.

(Note: All product names and trademarks remain consistent with manufacturer specifications.)