Device built-in

Cytiva Biacore™ T200 Molecular Interaction Analysis System Introduction

Product Overview
The Biacore™ T200 is a premium surface plasmon resonance (SPR) molecular interaction analysis system developed by Cytiva. Utilizing globally leading label-free real-time detection technology, it enables precise measurement of binding kinetics, affinity, and concentration between biomolecules. Renowned for its ultra-high sensitivity and automation, this system has become the gold standard in drug development, antibody characterization, and life science research.

Core Technological Advantages

1. Ultra-Sensitive Detection

   • Detection limit as low as 0.03 RU (resonance units), capable of analyzing compounds with molecular weights ≥100 Da.
   • Temperature control precision of ±0.005°C, ensuring highly stable experimental conditions.

2. Fully Automated High-Throughput

   • Integrated 96/384-well plate autosampler supports unattended continuous analysis of 192 samples.
   • Smart microfluidics system minimizes sample consumption to 5 µL per test.

3. Multifunctional Analysis

   • Simultaneously measures association/dissociation rate constants (ka/kd), affinity (KD), and thermodynamic parameters.
   • Supports antibody epitope binning, multivalent binding analysis, and complex matrix detection.

Typical Applications

• Drug Development: Candidate screening and optimization.
• Antody Engineering: Affinity maturation and cross-reactivity evaluation.
• Basic Research: Protein-nucleic acid interaction mechanism studies.

System Configuration

• Optical Module: High-resolution SPR optical detector.
• Temperature Control: Precise 4–45°C range.
• Data Analysis: Includes Biacore™ Evaluation Software for professional kinetic analysis.

Certified under ISO 13485, Biacore™ T200 data is directly admissible for FDA/EMA submissions, making it a core analysis platform spanning the entire biopharmaceutical pipeline—from discovery to quality control.

Note: "Biacore™" is a registered trademark of Cytiva. Specifications are based on manufacturer documentation. Let me know if you require further customization!