Device built-in

JEOL Auto Amino Acid Analyzer JLC-500/V2 Introduction

Product Overview

The JEOL Auto Amino Acid Analyzer JLC-500/V2 is a next-generation fully automated amino acid analyzer developed by JEOL Ltd. (Japan). Utilizing ion-exchange chromatography separation with post-column ninhydrin derivatization, it enables precise quantification of 20 standard amino acids in protein hydrolysates, food products, and biological samples. This system finds wide applications in food nutrition analysis, clinical diagnostics, and biopharmaceutical quality control.

Key Features

1. High-Precision Separation and Detection

   • Features high-resolution ion-exchange chromatography columns capable of baseline separation of all 20 standard amino acids, including challenging pairs like asparagine and glutamine
   • Offers detection limits as low as 5 pmol with a linear range of 0.1-100 nmol, meeting requirements for trace-level analysis

2. Fully Automated Operation

   • Equipped with an autosampler (optional 48/96 positions) supporting unattended continuous analysis
   • Incorporates an intelligent temperature control system for precise column (30-80°C) and reaction temperature (50-130°C) regulation

3. Smart Data Processing

   • Includes JLC-5000 workstation software with automated peak identification, quantitative calculation, and report generation capabilities
   • Complies with ISO 17025 standards and meets GLP/GMP data integrity requirements

4. Flexible Application Configurations

   • Optional physiological fluid analysis programs for clinical samples like plasma, urine, and cerebrospinal fluid
   • Supports various sample preparation methods for protein hydrolysates and food extracts

Technical Specifications

• Analysis Method: Ion-exchange chromatography with post-column ninhydrin derivatization
• Analysis Time: Approximately 60 minutes for standard program (optimizable to 30 minutes)
• Injection Volume: 10-100 μL (automatically adjustable)
• Detector: Dual-wavelength visible detector (440nm, 570nm)
• Data Output: Chromatograms, quantitative reports, standard curves

Conclusion

The JEOL JLC-500/V2, with its excellent resolution, automated operation, and intelligent analysis, stands as an ideal solution for amino acid analysis. Particularly suitable for food nutrition assessment, clinical metabolic research, and bioproduct quality control, it provides reliable and efficient amino acid analysis solutions for both research and industrial users. While maintaining JEOL's traditional reliability, the optimized design significantly enhances analysis throughput and data reliability. This system represents a perfect combination of Japanese precision engineering and advanced analytical technology, making it a preferred choice for laboratories requiring high-quality amino acid analysis.