Device built-in

Waters LC Module 30cm Column Oven Introduction

The Waters LC Module 30cm Column Oven is a critical temperature control component specifically designed by Waters Corporation for its high-performance liquid chromatography systems. Primarily used for precise regulation of chromatographic column operating temperatures, this device ensures separation process reproducibility and stability. Featuring a compact modular design, it seamlessly integrates with mainstream LC systems including Waters Alliance series and ACQUITY UPLC.

Core Technologies and Performance Parameters

The LC Module 30cm Column Oven employs advanced PID temperature control technology, offering a temperature range typically from ambient +5°C to 80°C (extendable to 4-65°C for certain models) with stability up to ±0.1°C, effectively eliminating environmental temperature fluctuations' impact on chromatographic separation. Its 30cm standard internal chamber accommodates most conventional analytical columns (e.g., 4.6mm ID columns) while maintaining compatibility with some narrow-bore and preparative columns.

The temperature control system features dual-path independent heating/cooling design, achieving heating rates up to 10°C/minute. Cooling is accomplished through high-efficiency thermoelectric coolers combined with forced air convection for rapid temperature equilibration. The built-in multi-segment programmable temperature function (supporting up to 11 gradient curves) meets complex method development requirements. An intuitive LED display on the front panel provides real-time monitoring of set temperature, actual temperature, and operational status.

System Integration and Intelligent Features

This column oven supports remote control and monitoring via Waters Empower or MassLynx software platforms, capable of storing up to 100 method parameter sets. Its innovative "hot-swappable" design enables column replacement without system shutdown, significantly improving workflow efficiency. The integrated pressure sensor (maximum pressure resistance 5000psi) automatically triggers safety protocols upon detecting abnormal pressure fluctuations.

As a key component of Waters modular LC systems, the 30cm column oven connects rapidly with other modules (e.g., autosamplers, detectors) through standardized interfaces. Optional column switching valve configurations (supporting automatic switching of up to six columns) dramatically enhance method development efficiency. Compliant with GLP/GMP regulations, the system incorporates audit trail functionality with full traceability for all temperature parameters and operational records.

Application Fields and Service Support

Widely utilized in pharmaceutical method development and stability studies; food safety testing for reproducible pesticide residue analysis; environmental monitoring to improve polar compound separation efficiency; and life science research for preserving biomolecule activity. Waters provides comprehensive technical support including installation qualification, periodic calibration, and preventive maintenance services to ensure long-term stable operation.

Rigorous validation confirms the LC Module 30cm Column Oven's exceptional temperature uniformity (internal chamber variation <±0.5°C) and reproducibility (continuous operation RSD<0.1%). Its reliable performance has established this unit as the preferred temperature control solution for numerous compliance-focused laboratories.