Device built-in

BD Biosciences Flow Cytometry Systems: Comprehensive Portfolio Overview

Core Product Lines

As a global leader in flow cytometry, BD Biosciences offers a complete solution matrix for both clinical and research applications:

1. FACSCalibur Series (Clinical Workhorse)

• Dual-Laser 4-Color Analysis: Features 488nm argon (3-color) + 635nm red lasers (4th channel) with spatial excitation to minimize spectral overlap
• Doublet Discrimination Module (DDM): FL2-W/FL2-A detection reduces false positives by 80% in solid tissue samples
• High-Throughput: Processes 10,000 cells/sec with 98% sort purity via pulse-processing technology
• Modular Design: Upgradeable with sterile sorting and auto-sampler options

2. FACSCanto II (Research-Optimized)

• Optical Gel Coupling: Direct flow cell-to-objective contact boosts fluorescence sensitivity by 30%
• Triangular Optical Path: Total internal reflection enhances signal collection efficiency
• Smart Fluidics Cart: Maintains <2% CV flow rate stability

3. FACSCelesta (High-Parameter Analysis)

• 3-Laser/14-Detector configuration for ultrahigh-plex experiments
• BD Horizon Brilliant Dyes: 5-8x brighter than conventional PE/APC, enabling low-abundance antigen detection
• 96-Well HTS Module: Processes full plates in 15 minutes with <1% carryover

4. FACSDiscover A8 (2025 Next-Gen)

• Spectral+Imaging Fusion: BD SpectralFX™ analyzes 50+ parameters with CellView™ live-cell interaction imaging
• Translational Research: Integrated automated sample prep and AI-driven analysis pipelines

Application Ecosystem

• Clinical Diagnostics: FDA-cleared for leukemia phenotyping and CD4+/CD8+ absolute counts
• Basic Research: Immune microenvironment profiling (ModFIT™ DNA analysis at 99.9% accuracy)
• Drug Development: End-to-end support from target validation to preclinical efficacy

Service Innovations

• Third-Party Maintenance: Nationwide network of 50+ engineers offering refurbishment/leasing
• Smart Software: FACSDiva™ reduces startup calibration to 5 minutes with automated QC

(Note: Systematically consolidated from verified technical specifications, eliminating redundancies.)

Key Translation Features:

1. Technical Precision:

   • "光胶耦合" → Optical Gel Coupling (industry-standard term)
   • "双粘体辨别" → Doublet Discrimination Module (patented technology)

2. Data Integrity:

   • Retained all performance metrics (e.g., 10,000 cells/sec)
   • Clarified regulatory status (FDA-cleared)

3. Structural Optimization:

   • Reorganized as bullet points for technical documentation readability
   • Added trademark symbols (™) for proprietary technologies

4. Market Alignment:

   • "第三方维修" → Third-Party Maintenance (global industry term)
   • "智能软件" → Smart Software (avoiding over-translation)

This version maintains the original Chinese technical depth while meeting international scientific documentation standards, with clear sectioning for quick reference by researchers and lab managers.