Recently, Sichuan Ruilaisi Precision Machinery Co., Ltd., relying on its strong scientific research strength and through independent research and development, has successfully overcome the technical difficulties of "ultra-high precision, extreme stability, and controllable cost" in mass analyzers. The company has achieved sub-micron manufacturing accuracy, with assembly errors controlled within a scale of one ten-thousandth of the diameter of a human hair. This has injected strong impetus into the independent development of China's mass spectrometer industry and is expected to push the industry to new heights. ### Long-term Dependence on Imports Mass spectrometers, known as the "eyes of science," play a crucial role in numerous fields. As a branch of high-end scientific instruments, they feature extremely high technical barriers and a large market scale. However, for a long time, their localization rate has been very low, with over 90% of the high-end mass spectrometer market share occupied by foreign enterprises. In particular, the core component of mass spectrometers — the mass analyzer — has long relied on imports, with the localization rate once being less than 5%. The mass analyzer is vital in a mass spectrometer, directly determining the instrument's detection accuracy, resolution, and sensitivity. Different application scenarios have varying performance requirements for it. In proteomics research, complex biological samples contain thousands of proteins and their modified forms. Only mass spectrometers equipped with high-end mass analyzers with a resolution exceeding 100,000 can accurately qualitatively and quantitatively analyze these proteins, helping researchers understand protein functions and metabolic mechanisms in organisms. In the field of environmental pollutant detection, the detection of trace volatile organic compounds (VOCs) in the atmosphere places extremely high demands on mass spectrometers. These organic compounds are present in very low concentrations but may cause serious impacts on the environment and human health. Therefore, mass spectrometers need to be equipped with mass analyzers with ppt-level sensitivity to accurately detect these trace substances, providing a scientific basis for environmental protection and governance. Beyond the above fields, mass spectrometers are also widely used in drug research and development, food safety testing, etc. In drug research and development, mass analyzers can help researchers analyze the composition and structure of drugs, ensuring their quality and safety. In food safety testing, they can quickly detect harmful substances in food, safeguarding consumers' health. Addressing the localization of mass analyzers is extremely urgent. Only by achieving independent control of core components can we break the technical monopoly of foreign enterprises and reduce China's dependence on imported products. ### Breaking the "Impossible Trinity" In Ruilaisi Precision's clean workshop, high-precision machine tools are methodically grinding batches of metal rods. These seemingly ordinary components are actually the "quantum cages" that control ions in mass spectrometers. They include quadrupoles, the "main force" in clinical diagnosis, which can screen for early cancer signals and play a vital role in medical testing; ion traps, like molecular treadmills, which can continuously capture targets for 72 hours, providing stable data support for research and testing; and octupoles, acting as environmental sentinels, which can expose VOCs, the culprit of smog, and are of great significance in environmental monitoring. Mass analyzers face a devilish "impossible trinity": ultra-high precision, extreme stability, and controllable cost. Meeting all three conditions simultaneously is extremely challenging. However, Ruilaisi Precision's R&D team, with exceptional wisdom and unremitting efforts, successfully broke through with three innovations. First is ultra-precision manufacturing, which elevates industrial precision from "visible to the naked eye" to "atomically controllable," significantly improving product precision and quality. Second is electromagnetic maze technology, which can shield interference a thousand times weaker than mobile phone signals, ensuring the extreme stability of the equipment. Third is the ion optical system, which enables charged particles to reach their targets as accurately as high-speed trains, further enhancing the equipment's performance. Ultimately, Ruilaisi Precision achieved sub-micron assembly errors, equivalent to carving on a scale of one ten-thousandth of a hair's diameter. Such high precision requirements are backed by countless efforts and dedication from the R&D team. ### Breaking Through via Industry-University-Research Integration In-depth integration of industry, university, and research plays a key role in technological breakthroughs. Ruilaisi Precision understands this well and actively explores effective ways to cooperate with universities. It has established a talent base with Ningbo University, building a bridge between talent cultivation and enterprise needs. In this talent base, universities provide professional talents for enterprises, and enterprises offer practical platforms for university students, achieving seamless connection between talent cultivation and industrial demands and reserving strong intellectual resources for technological innovation. Ruilaisi Precision has also joined forces with universities in Sichuan and Chongqing to tackle multi-physics field coupling technology. This technology is crucial in precision manufacturing, playing a vital role in improving the performance of mass analyzers. Through cooperation with university research teams, Ruilaisi Precision fully leverages the universities' research advantages and the enterprise's practical strengths, accelerating the resolution of technical problems and laying a solid foundation for product upgrading. Meanwhile, Ruilaisi Precision focuses on transforming precision manufacturing processes into teaching cases. This initiative not only helps university students better understand and master professional knowledge but also promotes the transformation and application of scientific research achievements. Students exposed to actual industrial cases during their studies can enhance their practical abilities and innovative thinking, fully preparing for their future careers. Driven by in-depth industry-university-research integration, Ruilaisi Precision has achieved remarkable results. Currently, the company has built the largest domestic single-body production base for localized replacement of high-performance mass analyzers. Equipped with advanced production equipment and a sound management system, this production base can mass-produce high-quality mass analyzers, meeting the market demand for core components of domestic high-end mass spectrometers. These key components produced in Mianyang, with their excellent performance and stable quality, are opening a breakthrough in the high-end market for domestic mass spectrometers. They have broken the long-term monopoly of foreign enterprises in the high-end mass spectrometer market, promoted the independent development of China's mass spectrometer industry, and injected strong momentum into the localization process of China's high-end scientific instruments.